Biochemical Effects of Dietary Piperazine on Galleria mellonella L. (Lepidoptera: Pyralidae) as a Model Organism

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dc.authoridTuncsoy, Benay/0000-0003-4361-3475
dc.contributor.authorSugecti, Serkan
dc.contributor.authorSefer, Nur Emine
dc.contributor.authorTuncsoy, Benay
dc.contributor.authorBuyukguzel, Ender
dc.contributor.authorBuyukguzel, Kemal
dc.date.accessioned2026-02-27T07:33:02Z
dc.date.available2026-02-27T07:33:02Z
dc.date.issued2025
dc.description.abstractInsecticides used to control pests are one of the most important causes of environmental pollution. Therefore, eco-friendly novel chemicals with low toxicity to mammals are investigated in pest management. In the present study, we investigated the effects of piperazine, a clinically important drug, on the model pest Galleria mellonella (Lepidoptera: Pyralidae). The experimental results showed that increasing concentrations of piperazine caused cell damage in G. mellonella hemolymph. Cell damage indicators, such as, aspartate transferase, alanine transferase, and lactate dehydrogenase levels were altered following exposure. Moreover, creatine kinase, alkaline phosphatase, amylase, gamma glutamyl transferase and acetylcholinesterase in larval hemolymph also were adversely affected. In overall, these findings demonstrate, these results show that well-adjusted piperazine concentrations as a potential alternative chemical for pest management.
dc.identifier.doi10.1007/s00128-025-04058-1
dc.identifier.issn0007-4861
dc.identifier.issn1432-0800
dc.identifier.issue5
dc.identifier.pmid40372492
dc.identifier.urihttp://dx.doi.org/10.1007/s00128-025-04058-1
dc.identifier.urihttps://hdl.handle.net/20.500.14669/4426
dc.identifier.volume114
dc.identifier.wosWOS:001489453300003
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSpringer
dc.relation.ispartofBulletin of Environmental Contamination and Toxicology
dc.relation.publicationcategoryMakale - Uluslararas� Hakemli Dergi - Kurum ��retim Eleman�
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20260302
dc.subjectEnvironmental pollution
dc.subjectTransferase enzymes
dc.subjectAcetylcholinesterase
dc.subjectPest control
dc.subjectAnthelmintic
dc.titleBiochemical Effects of Dietary Piperazine on Galleria mellonella L. (Lepidoptera: Pyralidae) as a Model Organism
dc.typeArticle

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