Determination of exposure to major iodide ion uptake inhibitors through drinking waters

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dc.authoridBILGIN, AYSE KEVSER/0000-0003-1508-5345
dc.authoridBoyaci Gunduz, Cennet Pelin/0000-0001-6409-0840
dc.authoridCengiz, Mehmet Fatih/0000-0002-6836-2708
dc.contributor.authorCengiz, Mehmet Fatih
dc.contributor.authorSen, Fatih
dc.contributor.authorBilgin, Ayse Kevser
dc.contributor.authorBoyaci-Gunduz, Cennet Pelin
dc.date.accessioned2025-01-06T17:37:31Z
dc.date.available2025-01-06T17:37:31Z
dc.date.issued2022
dc.description.abstractGoiter, abnormal enlargement of the thyroid gland, is a significant worldwide public health problem. Iodine deficiency is known as the most common cause. Iodine is actively transported as iodide ion (I-) using Sodium Iodide Symporter (NIS) and sufficient blocking of I- transportation prevents the synthesis of thyroid hormones. The transportation can be blocked by some polyatomic anions known as I- uptake inhibitors. Perchlorate (ClO4-), thiocyanate (SCN-) and nitrate (NO3-) are reported as the major I- uptake inhibitors and exposure could be through various routes. Drinking water is an important exposure route. Since water is essential to sustain life, drinking water safety is very important for the protection of public health. However, as a result of natural and human-based processes, water can be contaminated and contamination of drinking water is a global food safety problem due to causing significant health and environmental problemsIn that context, this study aims to determine exposure levels to I- uptake inhibitors that arise from drinking waters at five different districts in Antalya, Turkey. Collected water samples contained NO3- and ClO4- in the range of 0.86-47.42 mg/L and
dc.description.sponsorshipScientific and Technolog-ical Research Council of Turkey TUBITAK [113Z612]
dc.description.sponsorshipThe authors of this manuscript thank The Scientific and Technolog-ical Research Council of Turkey TUBITAK (113Z612) for the financial support of this research project.
dc.identifier.doi10.1016/j.envres.2021.112345
dc.identifier.issn0013-9351
dc.identifier.issn1096-0953
dc.identifier.pmid34774300
dc.identifier.scopus2-s2.0-85119022610
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.1016/j.envres.2021.112345
dc.identifier.urihttps://hdl.handle.net/20.500.14669/2259
dc.identifier.volume204
dc.identifier.wosWOS:000730784500005
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherAcademic Press Inc Elsevier Science
dc.relation.ispartofEnvironmental Research
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20241211
dc.subjectDrinking water
dc.subjectGoiter
dc.subjectSodium iodide symporter
dc.subjectNitrate
dc.subjectPerchlorate
dc.subjectThiocyanate
dc.titleDetermination of exposure to major iodide ion uptake inhibitors through drinking waters
dc.typeArticle

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