Wetting properties of blood lipid fractions on different titanium surfaces

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dc.authoridKoca-Unsal, Revan Birke/0000-0003-1540-983X
dc.contributor.authorKoca, Revan Birke
dc.contributor.authorGuven, Onur
dc.contributor.authorCelik, Mehmet Sabri
dc.contributor.authorFiratli, Erhan
dc.date.accessioned2025-01-06T17:36:21Z
dc.date.available2025-01-06T17:36:21Z
dc.date.issued2020
dc.description.abstractBackground Blood is the first tissue contacting the implant surface and starting the biological interactions to enhance osseointegration and stimulate bone formation with the progenitor cytokines, chemokines, and growth factors. The coagulation cascade initiates the first step of osseointegration between implant and neighboring tissues. The wound healing may be inadequate unless the blood wets the implant surface properly. Wettability is one of the most important features of the implant surface while lipid level constitutes a milestone that may change the energy of blood, which determines its distribution on implant material. Thus, the aim of this study was to evaluate the effect of lipid component of blood as cholesterol and its treatment on their wetting behavior of titanium surfaces. Methods Five surface groups were formed including grade 4 titanium-machined, grade 4 titanium-SLA, grade 4 titanium-SLActive, Roxolid-SLA, and Roxolid-SLActive. In healthy, hyperlipidemic, and treatment situations, blood was taken from eight rabbits and dropped to the disc surfaces. Contact angles were measured between the blood samples and disc surfaces. Results A significant difference was found between both machined and SLActive surfaces, SLA and SLActive surfaces in the hyperlipidemic period, and only Roxolid-SLA and SLActive surfaces during the treatment period. When evaluated according to time, only grade 4-machined and Grade 4-SLA surfaces showed a significant difference. Conclusions Our findings indicated that each period has its own characteristics and showed the importance of cholesterol in blood structure on applicability of implant surfaces.
dc.description.sponsorshipIstanbul University, Department of Scientific Research Projects [30641]
dc.description.sponsorshipIstanbul University, Department of Scientific Research Projects, Project No: 30641
dc.identifier.doi10.1186/s40729-020-00213-x
dc.identifier.issn2198-4034
dc.identifier.issue1
dc.identifier.pmid32399791
dc.identifier.urihttps://doi.org/10.1186/s40729-020-00213-x
dc.identifier.urihttps://hdl.handle.net/20.500.14669/1836
dc.identifier.volume6
dc.identifier.wosWOS:000532194300001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSpringer Japan Kk
dc.relation.ispartofInternational Journal of Implant Dentistry
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241211
dc.subjectAnimal model
dc.subjectCholesterol
dc.subjectContact angle
dc.subjectHyperlipidemia
dc.subjectImplant surface
dc.subjectStatin
dc.subjectWettability
dc.titleWetting properties of blood lipid fractions on different titanium surfaces
dc.typeArticle

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