Effects of Cu, Zn and their mixtures on bioaccumulation and antioxidant enzyme activities in Galleria mellonella L. (Lepidoptera: Pyralidae)
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Tarih
2022
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Springer
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
The effects of Cu, Zn and their mixture on bioaccumulation and antioxidant enzyme activities of midgut and fat body of Galleria mellonella larvae were investigated. Exposure to mixtures of both metals showed a synergistic effect and the accumulation levels were increased in both tissues. When the metals were exposed separately the concentration of Zn increased in both tissues, whereas the concentration of Cu increased in midgut and decreased in fat body. Also, it was determined that, oxidative stress occurred in the midgut and fat body when G. mellonella larvae were fed singly and in a mixture with different concentrations of Cu and Zn. In addition, significant changes were observed in antioxidant and detoxification enzyme activities, which are an indicator of oxidative stress. Larvae of G. mellonella showed immune responses similar to vertebrates, and could be used as bioindicator species due to being grown easily in the laboratory and reduced research costs Understanding the detoxification mechanism in insects is an important parameter for future ecotoxicological studies on the genotoxic, cytotoxic and physiological effects that different environmental pollutants such as heavy metals can cause.
Açıklama
Anahtar Kelimeler
Accumulation, Antioxidant enzyme, Galleria mellonella, Heavy metals
Kaynak
Ecotoxicology
WoS Q Değeri
Q2
Scopus Q Değeri
Q2
Cilt
31
Sayı
4
