Effect of polymer concentration in cryogelation of gelatin and poly (vinyl alcohol) scaffolds
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Tarih
2019
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Techno-Press
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
The aim of this study was to investigate the effect of total polymer concentration on the chemical structure, morphology of pores, porosity, swelling ratio, degradation of gelatin-poly (vinyl alcohol) (Gel-PVA) cryogel scaffolds. Porous cryogels were prepared with cryogelation technique by using glutaraldehyde as a crosslinker. Functional group composition of cryogels after crosslinking was investigated by Fourier Transform Infrared (FTIR). The morphology of cryogels was characterized via scanning electron microscopy (SEM) and porosity analysis. All of the cryogels had a porous structure with an average pore size between 45.58 +/- 14.28 and 50.14 +/- 4.26 mu m. The cryogels were biodegradable and started to degrade in 14 days. As the polymer concentration increased the swelling ratio, the porosity and the degradation rate decreased. Spongy and mechanically stable Gel-PVA cryogels, with tunable properties, can be potential candidates as scaffolds for tissue engineering applications.
Açıklama
Anahtar Kelimeler
gelatin, poly (vinyl alcohol), cryogel, scaffold, tissue engineering
Kaynak
Biomaterials and Biomechanics in Bioengineering
WoS Q Değeri
N/A
Scopus Q Değeri
Cilt
4
Sayı
1
