Determination of Neopterin as a Prognostic Indicator Using Neopterin-Imprinted Cryogel Membranes

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dc.contributor.authorZenger, Okan
dc.contributor.authorEren, Burcu
dc.contributor.authorArısoy, Pırıl
dc.contributor.authorÖzdaş, Sibel
dc.contributor.authorBaydemir Peşint, Gözde
dc.date.accessioned2025-01-06T17:29:57Z
dc.date.available2025-01-06T17:29:57Z
dc.date.issued2021
dc.description.abstractNeopterin (Neo) is thought of as a key biomarker for the diagnosis and prognosis of a wide variety of diseases associated with cellular immune response. Therefore, it has become a vital need to be able to specifically determine the Neo concentration in human serum. Molecularly imprinted cryogels have come into prominence among other affinity systems by combining advantages of Molecular Imprinting Technology (MIT) and cryogels. In this chapter, synthesis of novel Neopterin-imprinted cryogel membranes (Neo-mip), characterization studies of synthesized materials, and their use in the determination of Neo in human serum is described in detail. In addition, the evaluation of selective Neo adsorption properties of Neo-mip against competitors (Pterin and Glucose) is discussed. Neo-mip will come into prominence as important affinity materials for the selective Neo recognition in body fluids, prior to use in the health sector. © 2021, The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature.
dc.identifier.doi10.1007/978-1-0716-1629-1_15
dc.identifier.endpage181
dc.identifier.issn1064-3745
dc.identifier.pmid34410669
dc.identifier.scopus2-s2.0-85113679477
dc.identifier.scopusqualityQ4
dc.identifier.startpage171
dc.identifier.urihttps://doi.org/10.1007/978-1-0716-1629-1_15
dc.identifier.urihttps://hdl.handle.net/20.500.14669/1419
dc.identifier.volume2359
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherHumana Press Inc.
dc.relation.ispartofMethods in Molecular Biology
dc.relation.publicationcategoryKitap Bölümü - Uluslararası
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20241211
dc.subjectBiomarker
dc.subjectCryogel membranes
dc.subjectMolecular imprinting technique
dc.subjectNeopterin
dc.subjectPrognostic Indicator
dc.subjectSpecific determination
dc.titleDetermination of Neopterin as a Prognostic Indicator Using Neopterin-Imprinted Cryogel Membranes
dc.typeBook Chapter

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