Zinc Borate (ZnB)-Incorporated Electrospun Polycaprolactone (PCL) Fibers: Multifunctional Antimicrobial Materials

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dc.authoridÇapkın Yurtsever, Merve/0000-0001-7874-4016
dc.authoridIyigundogdu, Zeynep/0000-0003-2067-4822
dc.contributor.authorCapkin Yurtsever, Merve
dc.contributor.authorCetin, Ilayda Nur
dc.contributor.authorIyigundogdu, Zeynep
dc.date.accessioned2026-02-27T07:33:29Z
dc.date.available2026-02-27T07:33:29Z
dc.date.issued2025
dc.description.abstractIn this study, due to its multifunctional nature, zinc borate (ZnB) was incorporated into electrospun polycaprolactone (PCL) fibers in various concentrations (1.5%, 3.5%, 5%, wt%). The homogenous fiber morphology, the varying fiber diameter distribution, and the presence of ZnB in PCL fibers were shown by SEM/EDS and FTIR analysis. TGA analysis revealed that the addition of ZnB into the matrix enhanced the thermal stability of polymer as evidenced by an increase in the temperature at 10% mass loss (T10) from 365 degrees C to 390 degrees C. The fire-retardant performance of the PCL fibers, as assessed by the calculated limiting oxygen index (LOI), exhibited an improvement from 17.65 to 18.83 upon the incorporation of 5 wt% ZnB. Mechanical test results revealed that the tensile strength increased from 2.36 MPa to 3.46 MPa, while the Young's modulus decreased from 25.06 MPa to 17.99 MPa for PCL-Control and 5 ZnB-PCL fibers, respectively. ZnB-PCL fibers had potent antibacterial effects against both Gram-positive, Gram-negative, antibiotic-resistant bacteria, and fungal strains. Furthermore, cytocompatibility analysis using mouse fibroblast cells (L929) indicated that ZnB-PCL fibers supported cell adhesion, spreading and proliferation, even in 5 ZnB-PCL fibers containing the highest amount of ZnB. The development of a material that simultaneously exhibits broad-spectrum antimicrobial activity while supporting cell viability and proliferation is highly significant. In this context, the findings of this study suggest that ZnB-PCL fibers are promising candidates for wound dressings and tissue engineering scaffolds with improved mechanical and biological properties, as well as industrial fields requiring antimicrobial properties.
dc.description.sponsorshipTrkiye Bilimsel ve Teknolojik Arascedil;timath;rma Kurumu [TUBITAK 2209A/1919B012108234]
dc.description.sponsorshipTurkiye Bilimsel ve Teknolojik Ara & scedil;t & imath;rma Kurumu, TUBITAK 2209A/1919B012108234, & Idot;layda Nur Cetin.
dc.identifier.doi10.1007/s12221-025-01290-8
dc.identifier.issn1229-9197
dc.identifier.issn1875-0052
dc.identifier.urihttp://dx.doi.org/10.1007/s12221-025-01290-8
dc.identifier.urihttps://hdl.handle.net/20.500.14669/4599
dc.identifier.wosWOS:001642723500001
dc.indekslendigikaynakWeb of Science
dc.language.isoen
dc.publisherKorean Fiber Society
dc.relation.ispartofFibers and Polymers
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20260302
dc.subjectZinc borate
dc.subjectPolycaprolactone
dc.subjectElectrospun fibers
dc.subjectAntimicrobial
dc.subjectCytocompatibility
dc.titleZinc Borate (ZnB)-Incorporated Electrospun Polycaprolactone (PCL) Fibers: Multifunctional Antimicrobial Materials
dc.typeArticle; Early Access

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