Evaluation of ALSFRS-R Scale with Fuzzy Method in Amyotrophic Lateral Sclerosis

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dc.contributor.authorGül Koç, Gizem
dc.contributor.authorDağsuyu, Cansu
dc.contributor.authorKokangül, Ali
dc.contributor.authorKoç, Filiz
dc.date.accessioned2025-01-06T17:30:18Z
dc.date.available2025-01-06T17:30:18Z
dc.date.issued2022
dc.description.abstractIntroduction: Amyotrophic lateral sclerosis (ALS) is a disease with high morbidity and mortality that adversely affects the activities of daily living. Disease progression in ALS is characterized by loss of function in bulbar, motor, and respiratory parameters. The revised amyotrophic lateral sclerosis functional rating scale (ALSFRS-R), which consists of 12 criteria, is used to determine disease effects on each of these functions. While each criterion is equally important when calculating the total ALSFRS-R score, the importance levels of the 12 criteria may vary in clinical practice. In this classical approach, the relationships among the parameters are not considered and the effects of bulbar, spinal, and respiratory dysfunctions on a patient’s activities of daily living may be different. Methods: In this study, we aimed to evaluate ALS cases with the ALSFRS-R fuzzy method. Although each subheading in the ALSFRS-R had the same score, the disease score was determined by the fuzzy ALSFRS-R method, based on whether a subheading had priority in management of the disease. While creating the functional rating scale ALSFRS-R approach, fuzzy ALSFRS-R score values were obtained by creating fuzzy models for each main group and integrating the fuzzy model results of each main group into a separate model. Results: In total, 50 patients with definite ALS according to the El Escorial criteria (33 men [66%] and 17 women [34%]; mean age, 58.49±10.01 years) were included in the study. When ALSFRS-R results and fuzzy ALSFRS-R results were compared, the prioritization order of 45 patients increased using the fuzzy ALSFRS-R score, while the prioritization order of five patients remained the same in both evaluations. Conclusion: The approach obtained by using fuzzy membership functions and decision rules, formed in accordance with expert opinion, was applied to the data of 50 patients from a large-scale hospital. In total, 90% of the patients had increased prioritization when using the fuzzy ALSFRS-R scoring method. Our results showed that the fuzzy approach provided more accurate information regarding a patient’s condition. © 2020 by Turkish Association of Neuropsychiatry.
dc.identifier.doi10.29399/npa.27449
dc.identifier.endpage62
dc.identifier.issn1300-0667
dc.identifier.issue1
dc.identifier.scopus2-s2.0-85125266340
dc.identifier.scopusqualityQ3
dc.identifier.startpage54
dc.identifier.urihttps://doi.org/10.29399/npa.27449
dc.identifier.urihttps://hdl.handle.net/20.500.14669/1573
dc.identifier.volume59
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherTurkish Neuropsychiatric Society
dc.relation.ispartofNoropsikiyatri Arsivi
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241211
dc.subjectAmyotrophic lateral sclerosis
dc.subjectFunctional rating scale
dc.subjectFuzzy
dc.titleEvaluation of ALSFRS-R Scale with Fuzzy Method in Amyotrophic Lateral Sclerosis
dc.typeArticle

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