Influence of fabrication temperature on the structural features of chitosan gels for tissue engineering applications
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Tarih
2019
Yazarlar
Dergi Başlığı
Dergi ISSN
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Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Chitosan is a natural polymer synthesized from the chitin of crab, lobster shells, fungal myceliaand shrimp. It has been used for biomedical applications in many different structures includingthin film, nanofibrous membrane, sponge, microsphere, hydrogel and cryogel because of its nontoxicity, biodegradability, biocompatibility and antibacterial properties. Cryogelation technique isbased on the crosslinking of polymers or crosslinking polymerization of monomers in the presenceof crosslinking agents at temperatures below zero. On the other hand, hydrogels are mainlyprepared at room temperature. In this study, chitosan gels were prepared at different reactiontemperatures (-25, 0 and +25°C). Swelling profiles revealed that with decreasing reactiontemperature swelling ratio increased. In addition, the degradation rate of chitosan gels prepared at-25 and +25°C was measured 50.60 and 30.88%, respectively. Results indicate that reactiontemperature affects the architecture and characterization results of the gels.
Açıklama
Anahtar Kelimeler
Kaynak
International Advanced Researches and Engineering Journal
WoS Q Değeri
Scopus Q Değeri
Cilt
3
Sayı
3
