Phytochemical, Pharmacological, Phyto-cosmeceutical, Toxicity, and In silico Toxicological Evaluations of Vernonia amygdalina Delile – A Review

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dc.contributor.authorAtolani, Olubunmi
dc.contributor.authorBanerjee, Priyanka
dc.contributor.authorAyenı, Adedamola Elizabeth
dc.contributor.authorUsman, Muhammed Abubakar
dc.contributor.authorAdejumo, Opeyemi Jamiu
dc.contributor.authorErukaınure, Ochuko L.
dc.contributor.authorPreıssner, Robert
dc.date.accessioned2025-01-06T17:22:43Z
dc.date.available2025-01-06T17:22:43Z
dc.date.issued2024
dc.departmentAdana Alparslan Türkeş Bilim ve Teknoloji Üniversitesi
dc.description.abstractVernonia amygdalina Delile, which is in the Asteraceae family, is used as food and medicine all over the world, especially in Africa and Asia. This review reports the phytochemical, ethnopharmacological, phyto-cosmeceutical, and toxicological potentials of the plant. Recent scientific exploration of the plant has mainly focused on both its nutritional potential and ethnopharmacological properties. The antioxidant, anti-inflammatory, antidiabetic, hepatoprotective, hematological, anti-plasmodial, antimicrobial, anticancer, neurological, cosmeceutical, and other pharmacological values of V. amygdalina continue to be extensively explored. Many empirical studies of the therapeutic potential of the plant have attributed the ethnomedicinal properties of the plant to its phytochemical constituents, which include glycosides, saponins, tannins, terpenoids, etc. Compounds obtained from the leaves, root, stem, and flowers, which include vemoniosides, vernoamyosides, vernoniamyosides, vernoniosides, vernolide, vernodalol, vernodalin, vernomenin, vernomygdin, vernodalinol, epivernodalol, vernolepin, coumarins, luteolin, edotides, etc. have been identified as bioactive constituents responsible for numerous pharmacological activities of the plant. In addition, the toxicological evaluation of the plant revealed that it is safe for consumption at relatively high concentrations.
dc.identifier.doi10.18596/jotcsa.1247620
dc.identifier.endpage802
dc.identifier.issn2149-0120
dc.identifier.issue2
dc.identifier.startpage775
dc.identifier.trdizinid1241498
dc.identifier.urihttps://doi.org/10.18596/jotcsa.1247620
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1241498
dc.identifier.urihttps://hdl.handle.net/20.500.14669/473
dc.identifier.volume11
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofJournal of the Turkish Chemical Society, Section A: Chemistry
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241211
dc.subjectAntioxidant
dc.subjectbioactives
dc.subjectMedicinal plant
dc.subjectnutraceuticals
dc.subjectantidiabetic
dc.subjectvemoniosides
dc.titlePhytochemical, Pharmacological, Phyto-cosmeceutical, Toxicity, and In silico Toxicological Evaluations of Vernonia amygdalina Delile – A Review
dc.typeReview Article

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