Yazar "Kilincli, Betul" seçeneğine göre listele

Listeleniyor 1 - 3 / 3
  • [ X ]
    Öğe
    INVESTIGATION OF MACROELEMENT AND MINERAL VALUES IN BREAST MILK IN THE FIRST SIX MONTHS POSTPARTUM
    (Parlar Scientific Publications (P S P), 2021) Nazlican, Ersin; Kilincli, Betul; Yoldascan, Banu Elcin; Guzeler, Nuray; Abdul-Aziz, Abdul-Rashed
    Breast milk has the macro- and micro -nutrients required for the growth and development of a baby. There are very few studies that examine the relationship between breast milk mineral content and factors such as the mothers' physical. sociodemographic, and nutritional characteristics, As part of this research, breast milk samples were taken from volunteer mothers (excluding mothers with multiple births and premature births) in the first six months postpartum; pH. dry matter, ash, protein, fat, lactose, energy values and Fe, Ca, Mg. Cu, K, Zn, and Na contents were determined Breast milk samples were grouped into colostrum milk samples (n=10) and mature milk samples (n=40). It was shown that there is no relationship between mothers' B1\41 values and breast milk composition. With the findings obtained, it was determined that although the content profiles of breastmilk were variable, they still met the nutritional needs of babies.
  • [ X ]
    Öğe
    Microfluidic vs. batch synthesis of fluorescent poly(GMA-co-EGDMA) micro/nanoparticles for biomedical applications
    (Springernature, 2024) Kilincli, Betul; Cinar, Ayse Duru; Cetin, Barbaros; Kibar, Gunes
    Fluorescent particles play a crucial role in nanomedicine and biological applications such as imaging, diagnostic tools, drug delivery, biosensing, multimodal imaging, and theranostics. This report presents a novel synthesis method and comparative study for synthesizing fluorescent particles in microfluidic continuous and batch-type reactors. Glycidyl methacrylate (GMA) and ethylene glycol dimethyl acrylate (EGDMA) are well-known monomers for synthesizing functional particles for biomedical applications. Several methods exist to obtain fluorescent poly(GMA-co-EGDMA) (p(GMA-EGDMA))particles through various polymerization techniques. Unlike existing methods, we developed a green approach for synthesizing fluorescent p(GMA-EGDMA) particles via UV-initiated one-step emulsion polymerization by comparing microfluidic and batch synthesis. Moreover, as a fluorescent dye, fluorescein isothiocyanate (FITC) was directly incorporated with p(GMA-EGDMA) particles at various concentrations to achieve tunable fluorescent functionality. While the batch synthesis resulted in polydisperse fluorescent p(GMA-EGDMA)microparticles with spherical shapes ranging from 25 mu m to 1.0 mu m in size, the microfluidic synthesis produced nonspherical nanoparticles. Fluorescent FITC@p(GMA-EGDMA) particles were characterized by scanning electron microscope (SEM), fluorescent microscope, and Fourier-transform infrared spectroscopy (FTIR). The synthesized particles have potential for fluorescence imaging applications, specifically bio-detection in array systems.
  • [ X ]
    Öğe
    The risk estimation and assessment of heavy metal exposure by biomonitoring in the breast milk of mothers in the Cukurova Region, Turkey
    (Springer Heidelberg, 2022) Nazlican, Ersin; Arica, Enes; Goren, Ismail Ethem; Kilincli, Betul; Mete, Burak; Daglioglu, Nebile
    Toxic heavy metals released into the environment through various industrial processes have potential adverse effects on the environment and human health. In order to reveal these adverse health effects, it is vital to carry out toxicological studies by performing biomonitoring. This study aimed to assess the level of Cr, As, Cd, Hg, and Pb in the breast milk samples of mothers in the Cukurova region, Turkey, and its association with health risk to infants. Ten-milliliter postpartum milk samples were collected from 34 breast-feeding mothers in the first 2 months of their postpartum period and living in the Cukurova region, Adana. The measurement of target heavy metals levels was performed by using inductively coupled plasma mass spectroscopy (ICP-MS). The average breast milk levels of Cr, As, Cd, Hg, and Pb were 8.25, 1.64, 0.37, 2.60, and 12.12 mu g/L, respectively. Evaluation of breast milk samples for these toxic heavy metals revealed the high exposure level for Cr and As. However, the mothers who participated in the study were not occupationally exposed to these metals. This study showed that Cr, As, Cd, Hg, and Pb cross the placenta and blood-brain barrier prenatally and accumulate in breast milk postnatally.