• Development of Boron-Containing PVA-Based Cryogels with Controllable Boron Releasing Rate and Altered Influence on Osteoblasts 

  Ceylan, Seda; Dimmock, Ryan; Yang, Ying (POLYMERS / MDPI, 2023-04)

  Cryogel formation is an effective approach to produce porous scaffolds for tissue engineering. In this study, cryogelation was performed to produce boron-containing scaffolds for bone tissue engineering. A combination of ...
• Sainfoin (Onobrychis spp.) crop ontology: supporting germplasm characterization and international research collaborations 

  Karabulut, Ebrar; Erkoc, Kubra; Aci, Murat; Aydin, Mahmut; Barriball, Spencer; Braley, Jackson; Cassetta, Eric; Craine, Evan B.; Diaz-Garcia, Luis; Hershberger, Jenna; Meyering, Bo; Miller, Allison J.; Rubin, Matthew J.; Tesdell, Omar; Schlautman, Brandon; Sakiroglu, Muhammet (FRONTIERS IN PLANT SCIENCE / FRONTIERS MEDIA SA, 2023-03)

  Sainfoin (Onobrychis spp.) is a perennial forage legume that is also attracting attention as a perennial pulse with potential for human consumption. The dual use of sainfoin underpins diverse research and breeding programs ...
• Scaffolds from medical grade chitosan: A good choice for 3D cultivation of mesenchymal stem cells 

  Yurtsever, Merve Capkin; Akdere, Ozge Ekin; Gumusderelioglu, Menemse (TURKISH JOURNAL OF BIOLOGY / Scientific and Technological Research Council Turkey TUBITAK, 2022-01)

  Chitosan has high biocompatibility, supports proliferation of many cells, and can be a good carrier for various growth factors. However, low attachment ratio and spheroid formation of several stem cell types on plain ...
• Bioinformatics Prediction and Machine Learning on Gene Expression Data Identifies Novel Gene Candidates in Gastric Cancer 

  Kori, Medi; Gov, Esra (GENES / MDPI, 2022-12)

  Gastric cancer (GC) is one of the five most common cancers in the world and unfortunately has a high mortality rate. To date, the pathogenesis and disease genes of GC are unclear, so the need for new diagnostic and prognostic ...
• Developing Novel Antimicrobial and Antiviral Textile Products 

  Iyigundogdu, Zeynep Ustaoglu; Demir, Okan; Asutay, Ayla Burcin; Sahin, Fikrettin (APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY / SPRINGER, 2017-03)

  In conjunction with an increasing public awareness of infectious diseases, the textile industry and scientists are developing hygienic fabrics by the addition of various antimicrobial and antiviral compounds. In the current ...
• Nuclear entrapment of p33(ING1b) by inhibition of exportin-1: A trigger of apoptosis in head and neck squamous cell cancer 

  Ozdas, Sibel (CELLULAR AND MOLECULAR BIOLOGY / C M B ASSOC, 2018-04)

  The effect of deregulation of nuclear export mediated by exportin-L with consequent cellular mislocalization of p33(ING1b), a member of the tumor suppressor gene family, has not been previously investigated in head and ...
• Association of Toll-Like Receptor Polymorphisms With Nasal Polyposis 

  Kesici, Gulin Gokcen; Kaytez, Kargin Selda; Ozdas, Talih; Ozdas, Sibel (ENT-EAR NOSE & THROAT JOURNAL / SAGE PUBLICATIONS INC., 2021-01)

  Nasal polyposis is a disease characterized with chronic inflammation of the nasal mucosa. Toll-like receptors (TLRs) are defined as essential receptors of the innate immune system and may play in the development of nasal ...
• [Co-II(BPyPy2COH)(OH2)(2)](2+) A Catalytic Pourbaix Diagram and AIMD Simulations on Four Key Intermediates 

  Alberto, Roger; Iannuzzi, Marcella; Gurdal, Yeliz; Probst, Benjamin (CHIMIA / SWISS CHEMICAL SOCIETY, 2019-11)

  Proton reduction by [Co-II(BPyPy2COH)(OH2)(2)](2+)(BPyPy2COH = [2,2'-bipyridin]-6-yl-di[pyridin-2-yllmethanol) proceeds through two distinct, pH-dependent pathways involving proton-coupled electron transfer (PCET), reduction ...
• Identification of molecular signatures and pathways to identify novel therapeutic targets in Alzheimer's disease: Insights from a systems biomedicine perspective 

  Rahman, Md Rezanur; Islam, Tania; Zaman, Toyfiquz; Shahjaman, Md; Karim, Md Rezaul; Huq, Fazlul; Quinn, Julian M. W.; Holsinger, R. M. Damian; Gov, Esra; Moni, Mohammad Ali (GENOMICS / ACADEMIC PRESS INC ELSEVIER SCIENCE, 2020-03)

  Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized by the accumulation of amyloid plaques and neurofibrillary tangles in the brain. However, there are no peripheral biomarkers available that ...
• Impacts of Tourism-Led Constructions on Geoheritage Sites: the Case of Gilindire Cave 

  Aydin, Rozelin; Yuceer, Hulya (GEOHERITAGE / SPRINGER HEIDELBERG, 2020-05)

  Geological heritage sites are of great importance both for better understanding of the formation of the earth and for transferring its memory to future generations. People's curiosity to access this information leads to ...
• Co-expressed functional module-related genes in ovarian cancer stem cells represent novel prognostic biomarkers in ovarian cancer 

  Gov, Esra (SYSTEMS BIOLOGY IN REPRODUCTIVE MEDICINE / TAYLOR & FRANCIS INC, 2020-07)

  Ovarian cancer is the leading cause of death from gynecologic malignancies. Cancer stem cells (CSC) seem to play a crucial role in tumor metastasis, recurrence, and chemoresistance. Therefore, CSCs offer significant potential ...
• Pterostilbene protects cochlea from ototoxicity in streptozotocin-induced diabetic rats by inhibiting apoptosis 

  Ozdas, Sibel; Tastekin, Bora; Gurgen, Seren G.; Ozdas, Talih; Pelit, Aykut; Erkan, Sanem O.; Tuhanioglu, Birgul; Gulnar, Birgul; Gorgulu, Orhan (PLOS ONE / PUBLIC LIBRARY SCIENCE, 2020-07)

  Diabetes mellitus (DM) causes ototoxicity by inducing oxidative stress, microangiopathy, and apoptosis in the cochlear sensory hair cells. The natural anti-oxidant pterostilbene (PTS) (trans-3,5-dimethoxy-4-hydroxystylbene) ...
• Molecularly imprinted spongy columns for Angiotensin(II) recognition from human serum 

  Yildirim, Mehtap; Pesint, Gozde Baydemir (BIOTECHNOLOGY PROGRESS / WILEY, 2021-03)

  Angiotensin II (AngII), the effector peptide of the renin angiotensin system and has an important role in regulating cardiovascular hemodynamics and structure. AngII is an important biomarker for certain diseases that are ...
• Targeting the tumor stroma: integrative analysis reveal GATA2 and TORYAIP1 as novel prognostic targets in breast and ovarian cancer 

  Erceylan, Omer Faruk; Savas, Ayse; Gov, Esra (TURKISH JOURNAL OF BIOLOGY / TUBITAK SCIENTIFIC & TECHNICAL RESEARCH COUNCIL TURKEY, 2021-04)

  Tumor stroma interaction is known to take a crucial role in cancer growth and progression. In the present study, it was performed gene expression analysis of stroma samples with ovarian and breast cancer through an integrative ...
• Seed oil content and fatty acid profiles of endemic Phoenix theophrasti Greuter, Phoenix roebelenii O'Brien, Phoenix caneriensis Hort. Ex Chabaud, and Phoenix dactylifera L. grown in the same locality in Turkey 

  Ergun, Zeynep (TURKISH JOURNAL OF AGRICULTURE AND FORESTRY / TUBITAK SCIENTIFIC & TECHNICAL RESEARCH COUNCIL TURKEY, 2021-10)

  Plants-based oils and fats usually obtained from seeds have been indispensable substances for mankind, both in nutritional and industrial respect. This study aimed to determine the total amount of oil and the fatty acid ...
• Investigation of the Physiology of the Obligate Alkaliphilic Bacillus marmarensis GMBE 72(T) Considering Its Alkaline Adaptation Mechanism for Poly(3-hydroxybutyrate) Synthesis 

  Atakav, Yagmur; Pinar, Orkun; Kazan, Dilek (MICROORGANISMS / MDPI, 2021-02)

  The novel extreme obligate alkaliphilic Bacillus marmarensis DSM 21297 is known to produce polyhydroxybutyrate (PHB). However, the detailed mechanism of PHB synthesis in B. marmarensis is still unknown. Here, we investigated ...
• Identification of Common Pathogenetic Processes between Schizophrenia and Diabetes Mellitus by Systems Biology Analysis 

  Rahman, Md Rezanur; Islam, Tania; Nicoletti, Ferdinando; Petralia, Maria Cristina; Ciurleo, Rosella; Fisicaro, Francesco; Pennisi, Manuela; Bramanti, Alessia; Demirtas, Talip Yasir; Gov, Esra; Islam, Md Rafiqul; Mussa, Bashair M.; Moni, Mohammad Ali; Fagone, Paolo (GENES / MDPI, 2021-02)

  Schizophrenia (SCZ) is a psychiatric disorder characterized by both positive symptoms (i.e., psychosis) and negative symptoms (such as apathy, anhedonia, and poverty of speech). Epidemiological data show a high likelihood ...
• Bioinformatics and machine learning approach identifies potential drug targets and pathways in COVID-19 

  Auwul, Md Rabiul; Rahman, Md Rezanur; Gov, Esra; Shahjaman, Md; Moni, Mohammad Ali (BRIEFINGS IN BIOINFORMATICS / OXFORD UNIV PRESS, 2021-09)

  Current coronavirus disease-2019 (COVID-19) pandemic has caused massive loss of lives. Clinical trials of vaccines and drugs are currently being conducted around the world; however, till now no effective drug is available ...
• Genome-Wide Integrative Analysis Reveals Common Molecular Signatures in Blood and Brain of Alzheimer's Disease 

  Rahman, Md Rezanur; Islam, Tania; Shabjam, Md; Rana, Md Humayun Kabir; Holsinger, R. M. Damian; Quinn, Julian M. W.; Gov, Esra; Moni, Mohammad Ali (BIOINTERFACE RESEARCH IN APPLIED CHEMISTRY / BIOINTERFACE RESEARCH APPLIED CHEMISTRY, 2021-08)

  The currently utilized neuroimaging and cerebrospinal fluid-based detection of Alzheimers disease (AD) suffer several limitations, including sensitivity, specificity, and cost. Therefore, the identification of AD by analyzing ...
• Determination of Biochemical Contents of Fresh, Oven-Dried, and Sun-Dried Peels and Pulps of Five Apple Cultivars (Amasya, Braeburn, Golden Delicious, Granny Smith, and Starking) 

  Ergun, Zeynep (JOURNAL OF FOOD QUALITY / WILEY-HINDAWI, 2021-05)

  This study aimed to investigate the biochemical compounds of five different apple cultivars (Amasya, Braeburn, Golden Delicious, Granny Smith, and Starking) grown in the same location and to reveal the differences between ...

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