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Browsing by Author "Gokturk, Dilek"

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Adaçayı Bitkisinin Osteosarkoma (U-2 OS) Hücre Hattındaki Sitotoksik Etkisinin İncelenmesi

Gokturk, Dilek (Afyon Kocatepe Üniversitesi Fen ve Mühendislik Bilimleri Dergisi / Afyon Kocatepe Üniversitesi, 2018)

Adaçayı; Lamiaceae ailesine ait, aromatik, akdeniz kökenli bir bitkidir. Tüm dünyada, adaçayı, çeşitlihastalıklara deva bulmak ve hastalıklardan korunmak amacıyla yüzyıllardır geleneksel tedavidekullanılmaktadır. Adaçayı; ...
An alternative approach to tracing the volumic proliferation development of an entire tumor spheroid in 3D through a mini-Opto tomography platform

Polat, Adem; Gokturk, Dilek (MICRON / ELSEVIER, 2021-01)

Microscopy, which is listed among the major in-situ imaging applications, allows to derive information from a biological sample on the existing architectural structures of cells and tissues and their changes over time. ...
Glioblastoma hücre hattında (U87) siklopamin ve temozolomid kombine tedavisinin miR-20a ekspresyonu üzerine etkileri

Sencar, Leman; Yilmaz, Dervis Mansuri; Gokturk, Dilek; Ozandac Polat, Sema; Coskun, Gulfidan; Saker, Dilek; Sapmaz, Tugce; Kara, Samet; Celenk, Alper; Polat, Sait (Cukurova Medical Journal = Çukurova Üniversitesi Tıp Fakültesi Dergisi / Çukurova Üniversitesi, 2021-12)

Amaç: Bu çalışmada, glioblastoma hücre hattında (U87) siklopamin ve temozolomid (TMZ) tedavisinin ayrı ayrı ve kombine olarak uygulanmasından sonra miR-20a ekspresyonunun araştırılması ve bu miRNA’nın glioblastoma tedavisindeki ...
The Effect of Ascorbic Acid over the Etoposide- and Temozolomide-Mediated Cytotoxicity in Glioblastoma Cell Culture: A Molecular Study

Gokturk, Dilek; Kelebek, Hasim; Ceylan, Seda; Yilmaz, Dervis Mansuri (TURKISH NEUROSURGERY / TURKISH NEUROSURGICAL SOC, 2018)

AIM: Glioblastoma (GBM) is one of the lethal central nervous system tumors. One of the widely used chemical agents for the treatment of glioblastoma is temozolomide. It is an orally administered, deoxyribonucleic acid (DNA) ...
The Effect of Rosmarinus Officinalis and Chemotherapeutic Etoposide on Glioblastoma (U87 MG) Cell Culture

Ozdemir, Meryem Damla; Gokturk, Dilek (TURKISH NEUROSURGERY / TURKISH NEUROSURGICAL SOC, 2018)

AIM: To investigate whether high dose toxicities of etoposide can be overcome when used in combination with a natural compound named Rosmarinus Officinalis for glioblastoma (GBM). MATERIAL and METHODS: The impact of ...
Tracing 2D Growth of Pancreatic Tumoroids Using the Combination of Image Processing Techniques and Mini-Opto Tomography Imaging System

Akbaba, Cihat Ediz; Polat, Adem; Gokturk, Dilek (TECHNOLOGY IN CANCER RESEARCH & TREATMENT / SAGE PUBLICATIONS INC, 2023-07)

Objectives: In this study, we aimed to trace the 2D growth development of tumoroids produced with MIA PaCa-2 pancreatic cancer cells at different time points. Methods We cultured 3 different tumoroids with 0.5%, 0.8%, and ...

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